It doesn’t have to be creepy or problematic, but your son would have to know what worrying things to look out for. Nothing wrong with having a chat saying “hey just because large age gap friendships are rarer, i wanted to make sure you’re on your guard…but your friend might be awesome, just have your eyes open”.
What specifically worries you?
Let’s push it one step further and frame history since agriculture, 9500 years ago, against the upper limit of a human lifetime now, about 100 years. This would mean recorded times started only less than 100 human lifespans ago. Bleh